Twenty new cases are being reported this week, bringing the number of people infected to 481, according to San Diego County Health and Human Services.
Public Health Officer Wilma Wooten said there are 47 other cases awaiting confirmation.
Starting Wednesday, the Centers for Disease Control and Prevention will be in San Diego, discussing the spread of the virus, including how it made its way to Maricopa County in Arizona.
They will be presenting their findings at the 2017 ID week conference.
Dr. Wooten said San Diego has been working with the CDC for months.
"In May CDC sent staff here to work with us and help us identify the case definition," said Wooten. "We've been working with CDC as well as the State of California since we determined this outbreak."
The outbreak in San Diego was discovered last March.
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Wooten said the hepatitis outbreak could be slowing down, but right now it is just too early to tell.
