The capture of drug lord Joaquin Guzman was the crowning achievement of President Enrique Pena Nieto's government in its war against drug cartels, a beacon of success amid domestic woes. That makes the bold escape by "El Chapo" from a maximum security prison all the more devastating.
A widespread manhunt that included highway checkpoints, stepped up border security and closure of an international airport failed to turn up any trace of Guzman by Monday, more than 24 hours after he got away.
Widely considered the world's richest and most powerful drug trafficker before his capture last year, Guzman slipped down a shaft from his prison cell's shower area late Saturday and disappeared into a sophisticated mile-long (1.5 kilometer-long) tunnel with ventilation, lighting and a motorcycle apparently used to move dirt.
"All the accolades that Mexico has received in their counter-drug efforts will be erased by this one event" if Guzman is not recaptured, said Michael S. Vigil, a retired U.S. Drug Enforcement Administration chief of international operations.
More than anything else, the escape undermined Mexico's assertion it can deal with top drug lords at home and doesn't need to extradite them to the U.S. The national pride that appeared to motivate Pena Nieto's administration to prosecute drug lords like Guzman through its own court system has now turned into a national embarrassment.
"This is regrettable, very bad, because it without doubt affects the image of Mexico in the world," Mexican Sen. Luis Miguel Barbosa told journalists in Paris on Monday. He was part of a delegation traveling with the Mexican president to the French capital.
"You have to completely renew the Mexican prison system. The arrest of all warders and managers is not enough," he said. "This happened due to collaboration from within the jail at the highest level."
According to a report from the Congressional Research Service in May, extraditions from Mexico to the U.S. peaked at 115 in 2012, the last year of Pena Nieto's predecessor, Felipe Calderon. There were 66 last year.
The escape route apparently was built over the last year right under authorities' noses into a supposedly escape-proof lockup. Its scale has raised suspicions of corruption that could most discourage the U.S., Mexico's main ally that has poured more than $1 billion into joint efforts at battling organized crime cartels, much of it focused on reforming the criminal justice system.
The United States was already stinging from a court decision in August 2013 to free drug lord Rafael Caro Quintero on procedural grounds, overturning his conviction in the 1985 kidnapping, torture and murder of DEA agent Enrique "Kiki" Camarena. Caro Quintero hasn't been seen in public since then.
"For the most-wanted criminal to escape from the highest-security prison is going to create conflicts, the first of them with the United States," Mexican security expert Jorge Chabat said Sunday.
The escape also hurt Pena Nieto domestically. He had campaigned on one main promise — to diminish drug cartel violence — and had claimed success in attacking drug gang capos like no administration before, arresting or killing essentially all the top leadership of the Zetas, Beltran Leyva and Knights Templar cartels.
It was a highlight for an administration struggling on other fronts, including a lackluster economy and scandals over the disappearance of 43 college students, and the purchase by the president's wife of a mansion, known as the "white house," from a government contractor.
"This hurts him a lot. It is an administration that already has a lot of image problems, with the scandals over the students and the 'white house,' and now this comes along and paints them as an administration with serious problems of inefficiency and corruption," Chabat said.
Just as painful are memories of the cocksure way officials reacted after they captured Guzman in February 2014, some 13 years after the Sinaloa Cartel boss managed to flee from Mexico's only other maximum-security prison.
Pena Nieto said in a televised interview that allowing him to escape again would be "unforgiveable." Jesus Murillo Karam, his attorney general at the time, said the possibility of another Guzman escape "does not exist."
Manuel Ballbe, director of School of Risk Prevention at Spain's Autonomous University of Barcelona, said it was important for the U.S. to push for extraditions.
"International pressure is the check and balance against the state's corrupt powers," Ballbe said.
The bold and well-engineered escape also illustrates that simply capturing such a powerful figure without dismantling his financial network is insufficient, he said.
"Holding a drug lord inside the country does not affect his financial capacity," Ballbe said. "It is very difficult for the state to do something against the size of the bribes that these networks can produce."
U.S. Attorney General Loretta E. Lynch said in a statement that "we share the government of Mexico's concern regarding the escape of Joaquin Guzman," adding that "the U.S. government stands ready to work with our Mexican partners to provide any assistance that may help support his swift recapture."
But Peter Bensinger, a former administrator of the DEA, said he expects that U.S. officials have expressed their anger to their Mexican counterparts.
"He ought to have been housed in an American prison," Bensinger said. "Mexican authorities will come in for tremendous criticism, as they should."
Raul Benitez, a security expert at Mexico's National Autonomous University, said Guzman's second escape is even worse for Pena Nieto than if he had never captured him.
"In the context of the drug war it is the president's worst failure," Benitez said.
Everard Meade, director of the Trans-Border Institute, said Guzman's escape could mean changes to violence and smuggling practices along the border.
"There are a lot of ways in which you could hold El Chapo personally responsible for a lot of the violence in Tijuana, and a lot of the illicit trafficking coming across the border much more broadly over the last 15 years," he said.
His institute is offering peace-building training to non-governmental organizations in Culiacán, Sinaloa, that are working to provide youths with alternatives to entering the drug trade.
"The escape of El Chapo should give us an opportunity to take a closer look at them and wonder if maybe they'd make better partners for us as policy makers and as citizens in the United States than the Mexican government has proved," he said.