As speaker, the New York Democrat would be second in the presidential line of succession, after the vice president. He has vowed to focus on affordability and holding the administration accountable.
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The result is a crucial victory for Democrats in their push to retake the Senate majority, flipping a seat that Collins has held for nearly 30 years.
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The victories in the House and Senate return Democrats to full control of Congress for the first time since 2023 and deepens the level of expected friction between them and President Trump.
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Democrat Josh Turek has defeated Sen. Ashley Hinson in Iowa, according to a race call by the Associated Press.
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Democratic State Auditor Rob Sand stressed affordability and often talked about how his Christian faith guides him.
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Democratic former U.S. Sen. Sherrod Brown has won back a seat on Capitol Hill, defeating incumbent Republican Sen. Jon Husted after a close and expensive battle, according to a race call by the Associated Press.
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Democrat James Talarico has won the Senate seat in Texas, according to a race call by the Associated Press.
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The candidates tapped into voter frustration with the political status quo and will now look to translate their success into policy wins that push Democrats further to the left.
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Andrews, a pediatrician, defeated GOP Sen. Darline Graham, who was appointed to the seat after the death of her brother, longtime Sen. Lindsey Graham.
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The 29-year-old Ethiopian immigrant was one of several candidates to win with backing from the Democratic Socialists of America or its local chapters.
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Donalds, who was backed early by President Trump, will become the state's first Black governor.
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